April 4, 2013

ADH1 to Methanol to Formaldehyde

Posted in ASPARTAME tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , at 10:57 pm by PCOSLady

PCOS Lady:
Diabetics and most people are having their ADH1 levels checked yearly… This post explains what the ADH1 actually is… This is scary and may scare you straight! I hope you think twice about smoking and eating or drinking anything with aspartame in it…
~ “YOU” are choosing the rate you will die… Be it fast or slow…
~ Knowing all this, ask; How much does your health care professional care about you?
~
ADH1 to Methanol to Formaldehyde
~
http://rmforall.blogspot.com/2013/03/table-52-is-key-chart-adh1-enzyme-at.html
~
Table 5.2 is the key chart — ADH1 enzyme at high levels in 20 tissues in body and fetus makes methanol into formaldehyde right inside cells, initiating over 20 human diseases, with full text references, WC Monte paradigm: Rich Murray 2013.03.21
~
Table 5.2 is the key chart — ADH1 enzyme at high levels in 20 tissues in body and fetus makes methanol into formaldehyde right inside cells, initiating over 20 human diseases, with full text references, WC Monte paradigm: Rich Murray 2013.03.21
~
http://rmforall.blogspot.com/2013/03/table-52-is-key-chart-adh1-enzyme-at.html
~
[ See also:,
http://articles.mercola.com/sites/articles/archive/2013/03/13/unlabeled-aspartame-use.aspx#
2013.03.13 292,095 visits in a week ]
~
[ welcome to a scientific bouquet — some tasty dishes are presented twice… ]
~
A liter of diet drink gives the same methanol (wood alcohol) as the smoke from a pack of cigarettes, 60 mg — methanol has a half-life in the human bloodstream of 3 hours, showing that its elimination is slow, while it reaches every part of the body and the fetus every minute.
~
Methanol is actually less toxic than ethanol, except when it goes easily into cells that also happen to have high levels of free floating ADH1 enzyme, in 19 specific human tissues, including inner walls of blood vessels in the brain and eye, as well as in the rods and cones of the retina — the methanol is made quickly into free floating formaldehyde inside these cells, where it naturally wrecks havoc, interfering with all biochemistry, just as in its well known uses for embalming and sterilizing medical tools.
~
The resulting stew of formaldehyde modified proteins activates the inflammation process of the immune system, producing complex evolving pussy lesions — brain in Alzheimer’s and multiple sclerosis, inner walls of blood vessels in atherosclerosis, skin fibroblasts in lupus, pancreas in diabetes 2, retina in macular degeneration, joint fibroblasts in rheumatoid arthritis
~
Methylation of DNA and RNA leads to cell dysfunction and death, many later cancers, and birth defects, spina bifida, autism, preterm birth, Fetal Alcohol Sydrome.
~
Two key ATP enzymes are impaired in mitochrondria, shutting down aerobic energy metabolism, leading to reduced metabolism and anaerobic buildup of lactic acid, resulting in acidosis.
~
http://www.whilesciencesleeps.com/audio-book/
~
Table 5.2: Target Organs of Methanol Toxicity (Bad ADH1 Sites)
pages 60-1 “While Science Sleeps” textbook 2012 January, 236 pages,
Chapter 5 “The Silent Battle That Turns Methanol into Disease” —
~
The key chart that summarizes how ADH1 enzyme in high levels in 20 tissues in body and fetus makes methanol into formaldehyde right inside cells, initiating over 20 human diseases:
~
http://www.whilesciencesleeps.com/references/
~
7 ADH1 references (listed below) for 16 tissue types (some tissues have several diseases) 218, 220, 221, 357, 503, 514, 563, 637, 638, 640;
~
18 target tissues for formaldehyde harm;
~
Over 20 specific modern novel “diseases of civilization”;
~
Each with huge growth in incidence in the last 35 years — 25 references;
~
U shaped curve (those who never drink ethanol get twice the harm for 6 of these diseases as those who drink once daily, since ethanol is a potent antidote that prevents ADH1 from making methanol into formaldehyde) — 8 references;
~
18 diseases from smoking cigarettes (a strong methanol source) — 24 references;
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13 diseases from using aspartame — 22 references;
~
Monte didn’t have enough room on this 2-page figure to include the suite of 12 of the same symptoms and tissues from cases of often fatal chronic and acute methanol toxicity, page 133, with copious references.
~
This is a work in progress, highly incomplete, as this is an introductory update on the status of an breakthrough paradigm in toxicology, that presents multiple strong lines of evidence, allowing any intelligent layperson to come to their own decisions about methanol and resulting chronic formaldehyde toxicity diseases for specific high ADH1 sites, ranging from breast cancer to diabetes 2.
~
Table 5.2: target organs of methanol toxicity (bad ADH1 sites)
~
~ brain, vascular tissue, tau protein — Alzheimer’s myelin basic protein — multiple sclerosis
vascular lining — headache, seizures, glioblastoma cancer
~ eye, retina, ADH1 in rods and cones — macular degeneration
~ blood vessels, intima and media (inner walls), LDL low density lipoproteins — atherosclerosis
~ skin, fibroblasts — skin cancer, dermatitis, lupus (SLE systemic lupus erythematosus)
~ breast, epithelial (milk ducts) — adenocarcinoma
~ kidney, epithelial tubule — kidney cancer, poor function
~ bone, synovial fibroblast — rheumatoid arthritis
~ pancreas, islets of Langerhans — reduced insulin, diabetes 2
~ lung, fibroblasts — COPD chronic obstructive pulmonary disease, adenocarcinoma
~
Fetus, no ADH1 in placenta,
DNA methylation — terata (birth defects), autism
liver, lung, kidney harm — preterm delivery
~
Liver, highest ADH1 in body, many targets — hepatic cancer
~
“While Science Sleeps” textbook, 2012 January:
~
“Methanol travels easily to breast tissue and has been found in human milk. 219
~
The cells that produce milk within the breast, cells prone to develop
the most common of breast cancers, adenocarcinoma 358, contain high
levels of ADH1 enzyme, 358 allowing methanol’s conversion to
formaldehyde [ inside the cells as free floating acidic hydrated
formaldehyde, highly reactive on both sides of molecule ].
~
Mammary epithelial cells have no way to protect themselves from
formaldehyde 216 — no means to render it harmless.
~
They, unlike other breast tissue, contain no aldehyde dehydrogenase
enzyme (ADH 3) that could transform formaldehyde into the
non-carcinogenic formic acid. 216
~
Of particular interest are recent findings implicating ADH as playing
a pivotal role in the formation of breast cancer, documenting a
greater incidence of the disease in women with higher levels of ADH1
activity in their breasts. 357″
~
http://www.whilesciencesleeps.com/pdf/219.pdf
Labreche F, Goldberg M.
Exposure to Organic Solvents and Breast Cancer in Women: A Hypothesis.
American Journal of Industrial Medicine 1997;32:1-14.
~
http://www.whilesciencesleeps.com/pdf/358.pdf
Triano E, Slusher L, Atkins T, Beneski J, Gestl S.
Class I Alcohol Dehydrogenase Is Highly Expressed in Normal Human
Mammary Epithelium but not in Invasive Breast Cancer
: Implications for
Breast Carcinogenesis. Cancer Research Arch 2003;63:3092-100.
~
http://www.whilesciencesleeps.com/pdf/216.pdf
Crabb D, Matsumoto M, Chang D, You M.
Overview of the role of alcohol dehydrogenase and aldehyde
dehydrogenase and their variants in the genesis of alcohol-related
pathology
. Proceedings of the Nutrition Society 2004;63:49-63.
~
http://www.whilesciencesleeps.com/pdf/357.pdf
Coutelle C.
Risk Factors in Alcohol Associated Breast Cancer: Alcohol
Dehydrogenase Polymorphism and Estrogens
. International Journal of Oncology 2004;25:1127-32.
~
#6 diabetes 2 risk high for 2 cans aspartame diet drink weekly 14
years 66K women study
, Guy Fagherazzi et al AJCN 2013 Jan — methanol
(cigarettes, aspartame) formed into formaldehyde inside cells in
pancreas by ADH1 enzyme, WC Monte paradigm: Rich Murray 2013.02.13
http://rmforall.blogspot.com/2013/02/6-diabetes-2-risk-high-for-2-cans.html
~
The WC Monte January 2012 text is available at Amazon.com, “While
Science Sleeps”, low cost ebook, backed by his online archive of 745
free full text medical research references at WhileScienceSleeps.com ,
while two full chapters are free: Chapter 9, “Multiple Sclerosis” and
12, “Autism and Other Birth Defects.”
~
ADH1 is “unusually highly concentrated” in the million tiny “isles
of Langerhans” in the pancreas, where the beta cells make insulin —
cigarette use correlates with diabetes 2 risk, with a doubling of risk
for smoking over a pack daily.
[ page 172, “While Science Sleeps”, 2012 January, Prof. Woodrow C.
Monte, Food Science and Nutrition, Arizona State University, retired
2004 ]
~
WhileScienceSleeps.com includes free online archive of 745 full
text medical research references:
~
http://www.whilesciencesleeps.com/references/
~
http://www.whilesciencesleeps.com/pdf/637.pdf
Bühler R., Pestalozzi D., Hess M., Von Wartburg JP.
Immunohistochemical localization of alcohol dehydrogenase in human
kidney, endocrine organs and brain
.
Pharmacol Biochem Behav. 1983;
18 Suppl 1:55-9 1983;18(Suppl 1):55-9.
~
http://www.whilesciencesleeps.com/pdf/648.pdf
Willi C., Bodenmann P., Ghali WA., Faris PD., Cornuz J.
Active smoking and the risk of type 2 diabetes: a systematic review
and meta-analysis
.
JAMA 2007;298(22):2654-64.
~
http://www.whilesciencesleeps.com/pdf/283.pdf
Wei M, Gibbons L, Mitchell T, Kampert J, Blair S.
Alcohol intake and incidence of type 2 diabetes in men.
Diabetes Care 2000;23(1):16-21. Ming Wei mwei@cooperinst.org ]
~
Many of these diseases, including diabetes 2, are twice as harmful for
those who never drink ethanol, compared to those who have just one
standard drink a day, due to the inhibition by ethanol of formation of
formaldehyde from methanol by ADH1.
~
Many people are protected by methanol in their blood from fermentation by bacteria in the GI tract.
~
High levels of ADH1:
~ liver, kidney, lung;
~ intima and media (inner walls) of blood vessels, notably base of brain and retina;
~ rods and cones in retina;
~ purkinje cells of vermis in cerebellum;
~ islets of Langerhans in pancreas;
~ fibroblasts in skin, bone marrow, synovial tissues in joints;
~ milk ducts of breast;
~
Men have several times more ADH1 in their GI tract than women, so less methanol gets into the blood to attack other tissues, so now four times as many women get multiple sclerosis as men.
~
Sources of methanol (wood alcohol):
~ smoke from cigarettes, wood, peat;
~ aspartame, and chewing gums;
~ some dark wines and liquors;
~ fresh tomatoes, black currants;
~ unfresh fruits juices vegetables cut up and preserved wet at room temperature in sealed cans jars plastic containers (including home preserves and jugs of apple cider by farming families);
~ jams jellies marmalades;
~ smoked fermented spoiled foods;
~ some fresh coffees;
~ approved food additive dimethyl dicarbonate;
~ vehicle fuels;
~
Medical chemical mortuary facilities, home and industry solvents, factories for processed wood and paper products — formaldehyde heated to 150 deg C releases methanol…
~
http://www.whilesciencesleeps.com/pdf/475.pdf
Eng L. Localizations of Spacific Brain Antigens.
In: Boese A, editor. Search for the Cause of Multiple Sclerosis and other Chronic Diseases of the Central Nervous System.
Basel: Verlag Chemie; 1980. p. 15-460.
~
Search for the cause of multiple sclerosis and other chronic diseases of the central nervous system:
1. internat. symposion of Hertie Foundation in Frankfurt/Main, September 1979 / ed. by A.
Boese. — Weinheim, Deerfield Beach (Florida), Basel: Verlag Chemie, 1980.
ISBN 3-527-25875-2
~
Dr. Alfred Boese
GemeinnOtzige Hertie-Stiftung
Lyoner StraBe 15
D-6000 Frankfurt 71
~
http://www.whilesciencesleeps.com/pdf/218.pdf
Mori O, Haseba T, Kameyama K, Shimizu H.
Histological distribution of class III alcohol dehydrogenase in human brain.
Brain Research 2000;852:186-90.
mori-o@nms.ac.jp
~
http://www.whilesciencesleeps.com/pdf/220.pdf
Allili-Hassani A, Martinez S, Peralba J., et al.
Alcohol dehydrogenase of human and rat blood vessels:
Role in ethanol metabolism.
FEBS Letters 1997;405:26-30.
~
http://www.whilesciencesleeps.com/pdf/221.pdf
Buehler R, Hess M, Wartburg J.
Immunohistochemical Localization of Human Liver Alcohol Dehydrogenase in Liver Tissue, Cultured Fibroblasts, and HeLa Cells.
American Association of Pathologists 1982;108(1):89-99.
~
http://www.whilesciencesleeps.com/pdf/357.pdf
Coutelle C.
Risk Factors in Alcohol Associated Breast Cancer:
Alcohol Dehydrogenase Polymorphism and Estrogens. International Journal of Oncology 2004;25:1127-32.
Coutelle C, Höhn B, Benesova M, Oneta CM, Quattrochi P, Roth HJ, Schmidt-Gayk H, Schneeweiss A, Bastert G, Seitz HK. Department of Medicine
and Laboratory of Alcohol Research, Liver Disease and Nutrition,
Salem Medical Centre, Heidelberg, Germany.
~
http://www.whilesciencesleeps.com/pdf/503.pdf
Estonius M, Svensson S, Höög J.
Alcohol dehydrogenase in human tissues:
localisation of transcripts coding for five classes of the enzyme.
FEBS Lett. 1996;397:338-42.
~
http://www.whilesciencesleeps.com/pdf/514.pdf
Kinne R, Bräuer R, Stuhlmüller B, Palombo-Kinne E, Burmeste GR.
Macrophages in rheumatoid arthritis.
Arthritis Res 2000;2(3):189-202.
Raimund.W.Kinne@rz.uni-jena.de
[ no mention of ADH1 — the cause of RA is unknown… ]
~
SITES
~
GOOGLE:
aspartame
methanol
ethanol
formaldehyde
chronic formaldehyde toxicity diseases

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April 16, 2012

FYI – Medi Tid Bits

Posted in FYI BITS- MEDI tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , at 7:33 am by PCOSLady

KEEPING AN EYE ON ‘STUFF” FOR YOU!

FYI
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MEN
~
92% of men cheat for emotional reasons… Many of those women have hormone imbalances… See separate post in FYI – Tid Bits…
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WOMEN
~
http://health.yahoo.net/caring/are-you-about-to-have-a-heart-attack-7-heart-attack-signs-women-and-doctors-often-miss
~ Yahoo Health
~

HEART:   Have a Cardiac CT Scan ~ 3D view of your heart, 98% accurate …

~
CANCER
~
5/1/2012 Rachel Ray show…
Quote from Ryan O’Neal “Cancer loves sugar, (Farrah) she was starving on the inside”…
~
wwww.Mercola.com
~ Turmuric is king of spices, the pure turmuric powder… Not curry powder… It helps in preventing cancers …
~
IMPORTANT: Keep your vitamin D level high to fight cancer!
~
F.Y.I. ~ Cancer Centers of America create a treatment meant specifically for “YOU”!
~ I am serious, they truly care!
~
COPD ~ Found out recently if it reaches the 4th Phase you run the risk of lung cancer… In order to ward lung cancer off be sure your selenium level is at the proper level or abit above…
~ To much can be toxic!
~
POO – STOOL – #2
~
PCOS Lady:
Your body passes all bad stuff through your liver and out in your poo! Explains why we have to pay attention to it… Like it or not, looking could save your life!
~
http://www.continence.org.au/pages/bristol-stool-chart.html
FORUM: http://www.continence.org.au/forum/
~ Continence Foundation of Australia … Bristol Stool Chart …
~
CELLULITE
~
A woman just read the book Deep Nutrition: Why Your Genes Need Traditional Food. She was fascinated to learn that the reason we get cellulite is due to a lack of collagen…
~
SKIN, HAIR and NAILS
~
You need Keratin and Collagen to keep them all in great conditions…
~
MSG and Rosacea
http://www.msgtruth.org/rosacea.htm
~
Morgellons and GMO Foods
~ Bacterium is effecting humans…
~
YEAST
~
Yeast will leach out of your body through yeast infections… Breakouts experienced under breasts, in the groin, repeated yeast infections, etc… Do a yeast cleanse every 3 years!
~ Every antibiotic leaves yeast behind that will grow in you!
~ Bras may turn an off white, yellow, blueish or black in colors…
~ “Fishy” smell from your panty area… (Yeast or an STD)
~ Smell “fishy” under breast = yeast infection! You will see wet to blue to black staining on bra under your breast…Most likely from antibiotics through life… Do a yeast cleanse from a health store… Yeast is leaching out of you…
~
NAILS
~
Your finger nails will clue you in to some medical conditions…
~ Pitted means a lack of keratin…
~
HAIR
~
Marian once heard Dr. Judy, a talk show host who gives love/sex advice, say that hormones can cause *pubic* hair to be straight. She didn’t say what hormones.
~ http://faqpcos.com/pcos-symptoms/curly-hair-2369772.html
~
Hair loss can be from a vitamin deficiency… (Mercury poisoning, “bad” parasites, low testosterone levels, etc…)
~
Tabitha – Tabitha Takes Over TV show – 1/3/2012
~ For stressed out and hormonal thinning …. Viviscal Supplement- extra strength… $50
~ For gray – dull and blondes … Aveablue Malva Shampoo
~ For brittle unhealthy … Joico K Pak Revitaluxe … $22
~ Daily you can take GLA – 800 mgto add fat
~
Anemic Test: Look under your eye beneath your eye lid…
~ if red = good
~ if pink = anemic
~
Apple Cider Vinegar Spray for Dandruff
Combine ½ C of apple cider vinegar and ½ c of water into a spray bottle. Spritz onto the scalp and wrap head with a towel. Wait 15-minutes and then wash. The acid in the vinegar will break down the bacteria that dandruff thrives on. Do this 3 days in a row and then do for twice a week.
~ PCOS Lady: Knowing this is an ongoing thing it means what causing it in in you! “Bad” parasites come to my mind… www.ParasiteTesting.com
~
HYSTERECTOMY
~
Do you know some women have PCOS and do not need a hysterectomy? All because the doctor never tested all her hormones, etc…
~ True there are cases where because of PCOS a hysterectomy is needed…
~ I asked about this years ago in a forum and a woman confirmed 1st hand! (story in my blogdrive blog)
~ Question your tests and options, be sure!
~
METFORMIN:
~
– Metformin is the generic for the brand name Glucophage…Per Bristol Myers Squibb!
– IF anyone gets headaches or nausea from Metformin, stop taking it! Your body is rejecting the Met, it’s telling you it can’t tolerate the ingredients… Your doctors are lying to you saying its just your body getting used to the Met! Add Met to your list of allergic drugs….
– Docs get $ kickbacks, plus they may have no clue about Met!
– You should ask/demand Glucophage XR then, try it for a week or a month… You should not experience any ill symptoms!
~
DEPAKOTE
~
The legal limit for Depakote in your body is 100… If over by 3 points you will experience passing out, minor stroke symptoms that progress to sever stroke symptoms…
~ Have your drug levels checked when you have your blood tests done once a year atleast!
~ Doctors miss it and deem you a mental case (tough getting anywhere then unless a person – advocate helps) or misdiagnose you!
~
Valproate or divalproex (Depakote®), a drug used for epileptic seizures and some mood disorders, has been associated with a higher incidence of polycystic ovaries and hyperandrogenism.
~
http://www.wdxcyber.com/dxinf001.htm
~ Women’s Health Resource ….
~ *Google: Depakote PCOS …. Depakote hyperandrogenism
~
THYROID
~
~ IF
~ You’ve had thyroid surgery…
~ You’ve had treatment with radioactive iodine or anti-thyroid medications…
~ You’ve had radiation therapy to your head, neck or upper chest…
~ You need to have your thyroid checked periodically…
~ Consider checking your pituitary gland as well…
~
BREAST
~
Rare type of breast cancer without a lump: There is a less common form of breast cancer called inflammatory breast cancer. Its symptoms can be an inflammation of the breast tissue, such as with a breast rash with redness and warmth, but not necessarily a physical breast lump. This type of breast cancer should be considered as an uncommon possibility for certain types of breast symptoms…
~
http://www.breasthealthproject.com/breast-cysts.html

~ * Breast Health Project … FIBROCYSTIC BREASTS … LOOK and READ up on this…
~ “In holistic medicine and Chinese medicine theory, pain is caused by energy stagnation. People are always amazed at how easy it is to get the energy moving again. Movement in our breasts can effect a surprising amount of change.”
~
PREGNANCY DEFECTS
~
http://newyorkcity.injuryboard.com/medical-malpractice/us-docs-rarely-test-for-parasite-that-causes-miscarriage-premature-birth-and-congenital-birth-defects.aspx?googleid=300308
~
Scientists have identified the strains of the Toxoplasma Gondii parasite most often associated with miscarry, premature birth and birth defects, but testing of pregnant women in the United States is rare.
~
DIZZY
~
Feeling dizzy, light headed is a lack of blood or oxygen to your brain… A pulse ox meter will measure the oxygen at those times…
http://www.pulseoximeter.org/
~
DEPRESSION
~
Niacin No-Flush 500mg for depression…
~
CONSTIPATION
~
Magnesium Citrate, oral solution … Pasteurized sparkling laxative… Lemon or Cherry flavors … Drink a couple ounces or a full 10 ozs… Depends on your need…
~ It comes in a prescription at same strength…
~
MOUTH
~
Dr Oz ~ August 22, 2013 Show
~ Per Dentist
~ 600 species of bacteria are in your mouth…
~ Gum inflammation can cause inflammation in other body areas…
~ Gum disease to heart disease is possible!
~
Gum Disease and Other Systemic Diseases
~
Osteoporosis
Researchers have suggested that a link between osteoporosis and bone loss in the jaw. Studies suggest that osteoporosis may lead to tooth loss because the density of the bone that supports the teeth may be decreased, which means the teeth no longer have a solid foundation.
~
Respiratory Disease
Research has found that bacteria that grow in the oral cavity can be aspirated into the lungs to cause respiratory diseases such as pneumonia, especially in people with periodontal disease.
~
Cancer
Researchers found that men with gum disease were 49% more likely to develop kidney cancer, 54% more likely to develop pancreatic cancer, and 30% more likely to develop blood cancers.
~
Bacterial Endocarditis
Gum disease exists in about 75% of Americans, and many do not realize that risk factors associated with serious health concerns such as heart disease and stroke have been associated with gum disease. Researchers have found that people with gum disease are almost twice as likely to suffer from coronary artery disease. This type of heart disease occurs when plaques (deposits of fat, cholesterol, calcium and other material) form in the walls of the coronary arteries, causing the walls to become thicker. That essentially makes it harder for the blood to flow through, limiting the amount of oxygen and nutrients that are necessary for proper heart function.
~ Bacterial endocarditis is a dangerous infection that involves the lining of the heart and is commonly caused when bacteria enters the blood during medical procedures. During dental treatment, a common organism found in the mouth known as Streptococcus Viridan may enter the bloodstream and travel to the heart. This may cause infected blood clot formations that are able to travel to the brain, lungs, kidney, and spleen. Fifty percent of bacterial endocarditis cases are caused by Streptococcus Viridans.
~
TESTS:
~
HEART
Cardiac CT ~ 3D scan is 98% accurate
~
SITES
~
Oral Sex Smell of Bad Scent
http://www.diabeticconnect.com/discussions/10552-oral-sex-bad-scent-fungal-infections-and-metformin–delicate-embarrassing-question
~ Diabetic Connect by Alliance Health Community … Sick of having a smelly fungal rash under my breast. Even sicker about smelling fishy, I know that’s a sign of yeast infection but that …
~
Gum Disease and Heart Disease – Cardiovascular Disease
http://dentistry.about.com/od/issuesandemergencies/a/heartdisease.htm
~ dentistry.about.com › Health › Dental Care › Dental Emergencies ‎… Jan 23, 2011 – Gum Disease and Oral Hygiene May Be Connected to Heart … Bacterial endocarditis is a dangerous infection that involves the lining of the heart …
~ Usually requires heart surgery, not sure if the open way…
~
GOOGLE:
gum disease heart disease
bacterial endocarditis

More to come as i find interesting points…

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