December 4, 2012

Fungal Arthritis

Posted in FUNGAL tagged , , , , , , , , , , , , , , at 6:48 pm by PCOSLady

PCOS Lady:
Arthritis, many of you have it! Here is a fungal one you should look at and possibly ask your doctor to consider testing you for it!
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So often we accept our symptoms as being due to aging, body changing, hereditary things, etc…
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Fact is as we age we are experiencing foreign micro organisms (fungus, bacteria, “bad” parasites, yeast, etc…) invading us… Over the years they are showing signs they are in us!
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FUNGAL ARTHRITIS
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What are Fungal infections?
Fungal infections are caused by microscopic plants (fungi) that can live on the skin. They can live on the dead tissues of the hair, nails, and outer skin layers.
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http://adam.about.net/encyclopedia/infectiousdiseases/Fungal-arthritis.htm
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Fungal Arthritis
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Fungal arthritis is infection of a joint by a fungus.
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Causes:
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Fungal arthritis, also called mycotic arthritis, is a very rare condition. It can be caused by any of the invasive types of fungi. These organisms may affect bone or joint tissue. One or more joints may be affected, most often the large, weight-bearing joints, especially the knees.
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Conditions that can cause fungal arthritis include:
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~ Blastomycosis
~ Candidiasis
~ Coccidioidomycosis
~ Cryptococcosis
~ Histoplasmosis
~ Sporotrichosis
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The infection sometimes occurs as a result of an infection in another organ such as the lungs, and tends to get worse very slowly. The large joints are most often affected. People with weakened immune systems who travel or live in endemic areas are more susceptible to most causes of fungal arthritis.
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Symptoms:
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~ Arthritis
~ Fever
~ Joint pain
~ Joint stiffness
~ Joint swelling
~ Swelling of the ankles, feet, and legs
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Exams and Tests:
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~ Culture of joint fluid that grows fungus
~ Joint x-ray showing joint changes
~ Positive antibody test (serology) for fungal disease
~ Synovial biopsy showing fungus
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Treatment
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The goal of treatment is to cure the infection using antifungal drugs. The most commonly used antifungal drugs are amphotericin B or medications in the azole family (fluconazole, ketoconazole, or itraconazole).
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Chronic or advanced bone or joint infection may require surgery (debridement) to remove the infected tissue.
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Outlook (Prognosis)
What happens depends on the underlying cause of the infection and the patient’s overall health. A weakened immune system, cancer, and certain medications can affect the outcome.
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Possible Complication:
Joint damage can occur if the infection is not treated promptly.
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When to Contact a Medical Professional:
Call for an appointment with your health care provider if you have any symptoms of fungal arthritis.
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Prevention:
Thorough treatment of fungal infections elsewhere in the body may help prevent fungal arthritis.
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References:
~ Espinoza LR. Infections of bursae, joints, and bones. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 293.
~ Ohl CA. Infectious arthritis of native joints. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Churchill Livingstone Elsevier; 2009: chap 102.

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March 27, 2012

Hypopituitarism Pituitary Insufficiency

Posted in FATIGUE, RELATED: HORMONES tagged , , , , , , , , , , , , , , , , , , , , at 9:18 pm by PCOSLady

Hypopituitarism Pituitary Insufficiency
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Pituitary insufficiency post is important since many people are having radiation, brain surgery, etc… today… You may not be told of the long after effects that can occur in you!
~ … My close friend had a deadly cancer removed from his sinus cavity (under eye) a few years ago… The fatigue and pituitary symptoms started two years ago… The symptoms are now progressing real quick! He was up 24/7 now he just wants or has to sleep like 24/7…
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Hypopituitarism
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Pituitary Insufficiency
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Hypopituitarism is a condition in which the pituitary gland does not produce normal amounts of some or all of its hormones.
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Causes, incidence, and risk factors
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The pituitary gland is a small structure that is located just below the brain. It is attached by a stalk to the hypothalamus, the area of the brain that controls its function.
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The hormones released by the pituitary gland (and their functions) are:
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~ Adrenocorticotropic hormone (ACTH) — stimulates the adrenal gland to release cortisol; cortisol helps to maintain blood pressure and blood sugar
~ Antidiuretic hormone (ADH) — controls water loss by the kidneys
~ Follicle stimulating hormone (FSH) — controls sexual function and fertility in males and females
~ Growth hormone (GH) — stimulates growth of tissues and bone
~ Luteinizing hormone (LH) — controls sexual function and fertility in males and females
~ Oxytocin — stimulates the uterus to contract during labor and the breasts to release milk
~ Prolactin — stimulates female breast development and milk production
~ Thyroid stimulating hormone (TSH) — stimulates the thyroid gland to release hormones that affect the body’s metabolism
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In hypopituitarism, there is a lack of one or more pituitary hormones. Lack of the hormone leads to loss of function in the gland or organ that it controls. For example, no TSH leads to loss of function in the thyroid gland.
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Hypopituitarism may be caused by:
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~ Brain surgery
~ Brain tumor
~ Head trauma
~ Infections of the brain and the tissues that support the brain
~ Radiation
~ Stroke
~ Subarachnoid hemorrhage (from a burst aneurysm)
~ Tumors of the pituitary gland or hypothalamus
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Occasionally, hypopituitarism is due to uncommon immune system or metabolic diseases, such as:
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~ Hemochromatosis
~ Histiocytosis X
~ Lymphocytic hypophysitis
~ Sarcoidosis
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Hypopituitarism is also a rare complication after pregnancy, a condition called Sheehan’s syndrome.
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Symptoms
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~ Abdominal pain
~ Decreased appetite
~ Decreased sexual interest (in men)
~ Failure to release milk (in women)
~ Fatigue
~ Headache
~ Infertility (in women)
~ Lack of sex drive (in women)
~ Loss of armpit or pubic hair
~ Loss of body or facial hair (in men)
~ Low blood pressure
~ Sensitivity to cold
~ Short height (less than 5 feet) if onset is during a growth period
~ Slowed growth and sexual development (in children)
~ Stopping of menstrual periods (in women)
~ Vision problems
~ Weakness
~ Weight loss
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Note: Symptoms may develop slowly and may vary greatly, depending upon:

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~ The number of hormones that are missing and the organs they affect
~ The severity of the disorder
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Other symptoms that may occur with this disease:
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~ Face swelling
~ Hair loss
~ Hoarseness or changing voice
~ Joint stiffness
~ Weight gain (unintentional)
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Signs and tests
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To diagnose hypopituitarism, there must be low hormone levels due to a problem with the pituitary gland. The diagnosis must also rule out diseases of the organ that is affected by this hormone.
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Tests include:
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~ Brain CT scan
~ Pituitary MRI
~ Serum ACTH
~ Serum cortisol
~ Serum estradiol (estrogen)
~ Serum follicle stimulating hormone (FSH)
~ Serum insulin-like growth factor 1 (IGF-1)
~ Serum luteinizing hormone (LH)
~ Serum testosterone level
~ Serum thyroid stimulating hormone (TSH)
~ Thyroid hormone (T4)
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Levels of a pituitary hormone may be high in the bloodstream if you have a pituitary tumor that is producing too much of that hormone. The tumor may crush other cells of the pituitary, leading to low levels of other hormones.
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Source
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http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001383/
~ A.D.A.M. Medical Encyclopedia
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Google:
hypopituitarism
pituitary insufficiency
brain mass causing pcos

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