February 7, 2013

Metabolism Plateau

Posted in LIFESTYLE CHANGES tagged , , , , , , , , , , , , , , , , , at 5:41 pm by PCOSLady

PCOS Lady:
Many of us will hit a plateau, stuck in losing, a block, etc… You just have to try different things to get over it and keep losing weight…
~
Issues and factors do play a roll in this for some people…
~ Aging is a natural thing and can pack on pounds making you think you did something wrong or hit a plateau…
~ Drugs for high blood pressure, especially diuretics and the drugs known as beta-blockers, can make your body extremely resistant to weight loss… Cholesterol-lowering statin drugs also keep you from losing weight and they’re potentially dangerous as well… Dr. Atkins, “The majority of oral medications for diabetes have a weight-gain effect. The one drug that does help diabetics control their blood sugar and lose weight is metformin, marketed under the brand name Glucophage®.
~
http://www.low-carb.com/at-art5.html
~ Low-Carb … Informative on breaking your plateau…
~
Jacqueline Eberstein, R.N., director of medical education at The Atkins Center, figure out if you really are on a plateau. “The scale is the least reliable reflection of fat loss, ” she points out. “Look at other markers. Are you feeling better? Do your clothes feel loser? If you’re losing inches but not pounds, your fat cells are still shrinking. Also, check whether you are in still in lipolysis/ketosis by using ketone test strips. You’re only on a plateau it there’s no change at all for more than four weeks.”
~
http://www.low-carb.com/ketonestrips.html
~ Ketone Test Strips
~
Dr Oz
Overcome Your Metabolism Slump
~ Lose 20lbs in 4 weeks
Overcome Your Metabolism Slump
http://www.doctoroz.com/episode/overcome-your-metabolism-slump#cmpid=em020713
~ Dr Oz … Overcome Your Metabolism Slump – video peek … Lose 20lbs in 4 weeks … Aired 2/7/13 & 2/7/13 … A top nutritionist reveals the real reason why you’re not losing weight – and it’s not your fault! Get the three-phase plan to boost your metabolism and jump start your weight loss!
~
Dr Haylie Pomroy ~ https://www.facebook.com/hayliepomroy … Book: “The fast Metabolism Diet”
~ http://www.fastmetabolismdiet.com/
~
Dr Frances Largeman Roth ~ https://www.facebook.com/frances.largemanroth
~ www.franceslargemanroth.com/
~
Overcome Your Metabolism Slump | The Dr. Oz Show
www.doctoroz.com/episode/overcome-your-metabolism-slump
~ Dr Oz … Show episode …
~
http://www.tv.com/shows/the-dr-oz-show/episodes/
– Jumpstart Your Body – Metabolism one…
~
GOOGLE:
Dr Haylie Pomroy
Dr Frances Largeman Roth
fast metabolism diet
the fast metabolism diet
diet plateau
metabolism plateau
diet plateau meds
weight loss plateau
weight loss plateau tips

May 25, 2012

Diabetes

Posted in DIABETES tagged , , , , , , at 6:19 pm by PCOSLady

http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002194/
~
PCOS Lady:
Realizations are;
~ The US wants everyone to be Diabetic! (on a statin drug)
~ Your doctor loves you once he diagnosis you with Diabetes… You will be his lifelong patient!
~ Some Diabetes can be reversed, made less of a problem, etc…
~ Some people are born naturally Diabetic no matter what they try…
~
I suggest keeping up on ongoing research, join forums and groups… Plus change your lifestyle if you need to for your health…
~ Valuable info, tips, ways, etc… is found in 1st hand experiences, forums and groups…
~ Surgeries i am in favor of after trying non invasive methods…
~ BE SURE to have all your hormone levels checked… Check your mineral levels… Check your Serum Insulin level… Check your nutrient levels… BE SURE 1st before surgery please!
~
FYI
~
~ Mefformin is the generic for brand name Glucophage!
~ Doctors and pharmacies push Metformin, refuse it or try it for a week or two…
~ Metformin may cause discomfort as in headache and/or nausea in most people… Headaches are your body telling you its allergic or does not like the drug! (Budweiser is the only beer with many chemicals in it! Most people get headaches every time they drink it! Hmmmm!)
~
Recommended reading: Medicines for Type 2 Diabetes: A Review of the Research for Adults
~
This summary covers the research on the benefits and possible side effects of medicines to lower or control your blood sugar. It will help you talk with your doctor or other health care professional to decide which medicines are best for you.
~
A.D.A.M. Medical Encyclopedia
~
Diabetes
~
Last reviewed: August 31, 2011.
Diabetes is a lifelong (chronic) disease in which there are high levels of sugar in the blood.
~
See also:
~
~ Gestational diabetes
~ Metabolic syndrome
~ Type 1 diabetes
~ Type 2 diabetes
~
Causes, incidence, and risk factors
~
Insulin is a hormone produced by the pancreas to control blood sugar. Diabetes can be caused by too little insulin, resistance to insulin, or both.
~
To understand diabetes, it is important to first understand the normal process by which food is broken down and used by the body for energy. Several things happen when food is digested:
~ A sugar called glucose enters the bloodstream. Glucose is a source of fuel for the body.
~ An organ called the pancreas makes insulin. The role of insulin is to move glucose from the bloodstream into muscle, fat, and liver cells, where it can be used as fuel.
~
People with diabetes have high blood sugar because their body cannot move sugar into fat, liver, and muscle cells to be stored for energy. This is because either:
~
~ Their pancreas does not make enough insulin
~ Their cells do not respond to insulin normally
~ Both of the above
~
There are three major types of diabetes. The causes and risk factors are different for each type:
~
~ Type 1 diabetes can occur at any age, but it is most often diagnosed in children, teens, or young adults. In this disease, the body makes little or no insulin. Daily injections of insulin are needed. The exact cause is unknown.
~ Type 2 diabetes makes up most of diabetes cases. It most often occurs in adulthood, but teens and young adults are now being diagnosed with it because of high obesity rates. Many people with type 2 diabetes do not know they have it.
~ Gestational diabetes is high blood sugar that develops at any time during pregnancy in a woman who does not have diabetes.
~
Diabetes affects more than 20 million Americans. Over 40 million Americans have pre-diabetes (early type 2 diabetes).
~
Symptoms
~
High blood sugar levels can cause several symptoms, including:
~
~ Blurry vision
~ Excess thirst
~ Fatigue
~ Frequent urination
~ Hunger
~ Weight loss
~
Because type 2 diabetes develops slowly, some people with high blood sugar have no symptoms.
~
Symptoms of type 1 diabetes develop over a short period of time. People may be very sick by the time they are diagnosed.
~
Signs and tests
~
A urine analysis may be used to look for high blood sugar. However, a urine test alone does not diagnose diabetes.
~
Your health care provider may suspect that you have diabetes if your blood sugar level is higher than 200 mg/dL. To confirm the diagnosis, one or more of the following tests must be done.
~
Blood tests:
~ Fasting blood glucose level — diabetes is diagnosed if it is higher than 126 mg/dL twice. Levels between 100 and 126 mg/dL are called impaired fasting glucose or pre-diabetes. These levels are risk factors for type 2 diabetes.
~
~ Hemoglobin A1c test —
~ Normal: Less than 5.7%
~ Pre-diabetes: 5.7% – 6.4%
~ Diabetes: 6.5% or higher
~
~ Oral glucose tolerance test — diabetes is diagnosed if glucose level is higher than 200 mg/dL after 2 hours. (This test is used more often for type 2 diabetes.)
~
Screening for type 2 diabetes in people who have no symptoms is recommended for:
~
~ Overweight children who have other risk factors for diabetes, starting at age 10 and repeated every 2 years
~ Overweight adults (BMI greater than 25) who have other risk factors
~ Adults over age 45, repeated every 3 years
~
SITES
~
www.diabetes.org
~ The American Diabetes Association is leading the fight against the deadly consequences of diabetes and fighting for those affected by diabetes…
~
www.mayoclinic.com/health/diabetes/DS01121
~ Mayo Clinic … Diabetes — Comprehensive overview covers symptoms, causes and treatments of several types of diabetes…
~
www.Drugs.com
~ Drugs.com … Check all drugs, dosage, look, side effects, over the counter effects, brand name, generic, etc….
~
http://cholesterol.emedtv.com/statins/list-of-all-statin-drugs.html
~ MedTV … Nov 9, 2011 – Statins are commonly used to treat high cholesterol and prevent related health conditions. This eMedTV segment provides a complete list of all …
~
http://www.diabetesdaily.com/voices/2012/05/2-common-diet-habits-that-wont-help-you-lose-weight/?utm_source=MailingList&utm_medium=emailutm_campaign=DD+2012-05-23+You+Make+Diabetes+Look+Easy
~ Diabetes Daily … 2 common diet habits that don’t work! … Good source of info and a nice forum….
~
http://www.health.com/health/library/mdp/0,,std120744,00.html
~ Health.com … Info on Diabetes and what to do, etc…
~
www.jdrf.org
~ Juvenile Diabetes Research Foundation International
~
www.cdc.gov/diabetes/
~ National Center for Chronic Disease Prevention and Health Promotion
~
http://ndep.nih.gov/
~ National Diabetes Education Program
~
http://www.diabetes.niddk.nih.gov/
~ National Diabetes Information Clearinghouse (NDIC)
~
GOOGLE:
Diabetes
pre-diabetes
*statin drug list*
type 1 diabetes
diabetes type 1
diabetes mellitus
diabetes symptoms
diabetes recipes
diabetes diet
hypoglycemia
insulin
normal blood sugar levels

April 16, 2012

FYI – Medi Tid Bits

Posted in FYI BITS- MEDI tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , at 7:33 am by PCOSLady

KEEPING AN EYE ON ‘STUFF” FOR YOU!

FYI
~
MEN
~
92% of men cheat for emotional reasons… Many of those women have hormone imbalances… See separate post in FYI – Tid Bits…
~
WOMEN
~
http://health.yahoo.net/caring/are-you-about-to-have-a-heart-attack-7-heart-attack-signs-women-and-doctors-often-miss
~ Yahoo Health
~

HEART:   Have a Cardiac CT Scan ~ 3D view of your heart, 98% accurate …

~
CANCER
~
5/1/2012 Rachel Ray show…
Quote from Ryan O’Neal “Cancer loves sugar, (Farrah) she was starving on the inside”…
~
wwww.Mercola.com
~ Turmuric is king of spices, the pure turmuric powder… Not curry powder… It helps in preventing cancers …
~
IMPORTANT: Keep your vitamin D level high to fight cancer!
~
F.Y.I. ~ Cancer Centers of America create a treatment meant specifically for “YOU”!
~ I am serious, they truly care!
~
COPD ~ Found out recently if it reaches the 4th Phase you run the risk of lung cancer… In order to ward lung cancer off be sure your selenium level is at the proper level or abit above…
~ To much can be toxic!
~
POO – STOOL – #2
~
PCOS Lady:
Your body passes all bad stuff through your liver and out in your poo! Explains why we have to pay attention to it… Like it or not, looking could save your life!
~
http://www.continence.org.au/pages/bristol-stool-chart.html
FORUM: http://www.continence.org.au/forum/
~ Continence Foundation of Australia … Bristol Stool Chart …
~
CELLULITE
~
A woman just read the book Deep Nutrition: Why Your Genes Need Traditional Food. She was fascinated to learn that the reason we get cellulite is due to a lack of collagen…
~
SKIN, HAIR and NAILS
~
You need Keratin and Collagen to keep them all in great conditions…
~
MSG and Rosacea
http://www.msgtruth.org/rosacea.htm
~
Morgellons and GMO Foods
~ Bacterium is effecting humans…
~
YEAST
~
Yeast will leach out of your body through yeast infections… Breakouts experienced under breasts, in the groin, repeated yeast infections, etc… Do a yeast cleanse every 3 years!
~ Every antibiotic leaves yeast behind that will grow in you!
~ Bras may turn an off white, yellow, blueish or black in colors…
~ “Fishy” smell from your panty area… (Yeast or an STD)
~ Smell “fishy” under breast = yeast infection! You will see wet to blue to black staining on bra under your breast…Most likely from antibiotics through life… Do a yeast cleanse from a health store… Yeast is leaching out of you…
~
NAILS
~
Your finger nails will clue you in to some medical conditions…
~ Pitted means a lack of keratin…
~
HAIR
~
Marian once heard Dr. Judy, a talk show host who gives love/sex advice, say that hormones can cause *pubic* hair to be straight. She didn’t say what hormones.
~ http://faqpcos.com/pcos-symptoms/curly-hair-2369772.html
~
Hair loss can be from a vitamin deficiency… (Mercury poisoning, “bad” parasites, low testosterone levels, etc…)
~
Tabitha – Tabitha Takes Over TV show – 1/3/2012
~ For stressed out and hormonal thinning …. Viviscal Supplement- extra strength… $50
~ For gray – dull and blondes … Aveablue Malva Shampoo
~ For brittle unhealthy … Joico K Pak Revitaluxe … $22
~ Daily you can take GLA – 800 mgto add fat
~
Anemic Test: Look under your eye beneath your eye lid…
~ if red = good
~ if pink = anemic
~
Apple Cider Vinegar Spray for Dandruff
Combine ½ C of apple cider vinegar and ½ c of water into a spray bottle. Spritz onto the scalp and wrap head with a towel. Wait 15-minutes and then wash. The acid in the vinegar will break down the bacteria that dandruff thrives on. Do this 3 days in a row and then do for twice a week.
~ PCOS Lady: Knowing this is an ongoing thing it means what causing it in in you! “Bad” parasites come to my mind… www.ParasiteTesting.com
~
HYSTERECTOMY
~
Do you know some women have PCOS and do not need a hysterectomy? All because the doctor never tested all her hormones, etc…
~ True there are cases where because of PCOS a hysterectomy is needed…
~ I asked about this years ago in a forum and a woman confirmed 1st hand! (story in my blogdrive blog)
~ Question your tests and options, be sure!
~
METFORMIN:
~
– Metformin is the generic for the brand name Glucophage…Per Bristol Myers Squibb!
– IF anyone gets headaches or nausea from Metformin, stop taking it! Your body is rejecting the Met, it’s telling you it can’t tolerate the ingredients… Your doctors are lying to you saying its just your body getting used to the Met! Add Met to your list of allergic drugs….
– Docs get $ kickbacks, plus they may have no clue about Met!
– You should ask/demand Glucophage XR then, try it for a week or a month… You should not experience any ill symptoms!
~
DEPAKOTE
~
The legal limit for Depakote in your body is 100… If over by 3 points you will experience passing out, minor stroke symptoms that progress to sever stroke symptoms…
~ Have your drug levels checked when you have your blood tests done once a year atleast!
~ Doctors miss it and deem you a mental case (tough getting anywhere then unless a person – advocate helps) or misdiagnose you!
~
Valproate or divalproex (Depakote®), a drug used for epileptic seizures and some mood disorders, has been associated with a higher incidence of polycystic ovaries and hyperandrogenism.
~
http://www.wdxcyber.com/dxinf001.htm
~ Women’s Health Resource ….
~ *Google: Depakote PCOS …. Depakote hyperandrogenism
~
THYROID
~
~ IF
~ You’ve had thyroid surgery…
~ You’ve had treatment with radioactive iodine or anti-thyroid medications…
~ You’ve had radiation therapy to your head, neck or upper chest…
~ You need to have your thyroid checked periodically…
~ Consider checking your pituitary gland as well…
~
BREAST
~
Rare type of breast cancer without a lump: There is a less common form of breast cancer called inflammatory breast cancer. Its symptoms can be an inflammation of the breast tissue, such as with a breast rash with redness and warmth, but not necessarily a physical breast lump. This type of breast cancer should be considered as an uncommon possibility for certain types of breast symptoms…
~
http://www.breasthealthproject.com/breast-cysts.html

~ * Breast Health Project … FIBROCYSTIC BREASTS … LOOK and READ up on this…
~ “In holistic medicine and Chinese medicine theory, pain is caused by energy stagnation. People are always amazed at how easy it is to get the energy moving again. Movement in our breasts can effect a surprising amount of change.”
~
PREGNANCY DEFECTS
~
http://newyorkcity.injuryboard.com/medical-malpractice/us-docs-rarely-test-for-parasite-that-causes-miscarriage-premature-birth-and-congenital-birth-defects.aspx?googleid=300308
~
Scientists have identified the strains of the Toxoplasma Gondii parasite most often associated with miscarry, premature birth and birth defects, but testing of pregnant women in the United States is rare.
~
DIZZY
~
Feeling dizzy, light headed is a lack of blood or oxygen to your brain… A pulse ox meter will measure the oxygen at those times…
http://www.pulseoximeter.org/
~
DEPRESSION
~
Niacin No-Flush 500mg for depression…
~
CONSTIPATION
~
Magnesium Citrate, oral solution … Pasteurized sparkling laxative… Lemon or Cherry flavors … Drink a couple ounces or a full 10 ozs… Depends on your need…
~ It comes in a prescription at same strength…
~
MOUTH
~
Dr Oz ~ August 22, 2013 Show
~ Per Dentist
~ 600 species of bacteria are in your mouth…
~ Gum inflammation can cause inflammation in other body areas…
~ Gum disease to heart disease is possible!
~
Gum Disease and Other Systemic Diseases
~
Osteoporosis
Researchers have suggested that a link between osteoporosis and bone loss in the jaw. Studies suggest that osteoporosis may lead to tooth loss because the density of the bone that supports the teeth may be decreased, which means the teeth no longer have a solid foundation.
~
Respiratory Disease
Research has found that bacteria that grow in the oral cavity can be aspirated into the lungs to cause respiratory diseases such as pneumonia, especially in people with periodontal disease.
~
Cancer
Researchers found that men with gum disease were 49% more likely to develop kidney cancer, 54% more likely to develop pancreatic cancer, and 30% more likely to develop blood cancers.
~
Bacterial Endocarditis
Gum disease exists in about 75% of Americans, and many do not realize that risk factors associated with serious health concerns such as heart disease and stroke have been associated with gum disease. Researchers have found that people with gum disease are almost twice as likely to suffer from coronary artery disease. This type of heart disease occurs when plaques (deposits of fat, cholesterol, calcium and other material) form in the walls of the coronary arteries, causing the walls to become thicker. That essentially makes it harder for the blood to flow through, limiting the amount of oxygen and nutrients that are necessary for proper heart function.
~ Bacterial endocarditis is a dangerous infection that involves the lining of the heart and is commonly caused when bacteria enters the blood during medical procedures. During dental treatment, a common organism found in the mouth known as Streptococcus Viridan may enter the bloodstream and travel to the heart. This may cause infected blood clot formations that are able to travel to the brain, lungs, kidney, and spleen. Fifty percent of bacterial endocarditis cases are caused by Streptococcus Viridans.
~
TESTS:
~
HEART
Cardiac CT ~ 3D scan is 98% accurate
~
SITES
~
Oral Sex Smell of Bad Scent
http://www.diabeticconnect.com/discussions/10552-oral-sex-bad-scent-fungal-infections-and-metformin–delicate-embarrassing-question
~ Diabetic Connect by Alliance Health Community … Sick of having a smelly fungal rash under my breast. Even sicker about smelling fishy, I know that’s a sign of yeast infection but that …
~
Gum Disease and Heart Disease – Cardiovascular Disease
http://dentistry.about.com/od/issuesandemergencies/a/heartdisease.htm
~ dentistry.about.com › Health › Dental Care › Dental Emergencies ‎… Jan 23, 2011 – Gum Disease and Oral Hygiene May Be Connected to Heart … Bacterial endocarditis is a dangerous infection that involves the lining of the heart …
~ Usually requires heart surgery, not sure if the open way…
~
GOOGLE:
gum disease heart disease
bacterial endocarditis

More to come as i find interesting points…

March 16, 2012

INFO: FYI, FACTS, LINKS

Posted in INFO PLUS tagged , , , , , , , , , at 2:11 am by PCOSLady

FACT ~ INFO ~ LINKS ~ FYI
~ ~ ~
FACTS:
* 2004 the AACE www.aace.com made PCOS a priority to doctors…
www.aace.com/pub/pdf/guidelines/PCOSpositionstatement.pdf
~
* PCOS is a syndrome… YOU only have to have 1 symptom to be diagnosed with it… Main ones are; irregular menses ~ excessive male patterned hair growth ~ polycystic ovaries ~ unable to get pregnant…
~
* Your body can not tolerate sugar or flour, therefore you wear it… Diets best for you are high in protein and complex carbs, snacks of protein… Another thing to always do is eat your carbs with protein to lose and maintain weight…
~
* PCOS treatments are as individual as PCOS symptoms are in every woman… One treatment will never work for every woman! * If one doesn’t work try another or combinations of things* (Most doctors do one thing and drop you, so it seems …
~ I hear this all the time)… Important to join the forum at http://www.pcosupport.org/
~
* Diabetic drugs have been proven by research to keep PCOS women from developing full blown Diabetes 2 !!! ~ My case: My insulin level hit 26 one time in all my tests, my MD doc put me on Glucophlage XR 500 mg/daily… (my regular ranges are 22-24)
~
* Metformin ( the generic)
most likely will make you ill or feel ill (upset stomach, headaches, etc…) … Doctors and pharmacies push and sneak this pill on you… REFUSE IT!!! DEMAND the Metformin ER, extended release or Glucophlage XR…
~ I love Glucophlage XR, the side effects are pluses for me…
~
* PCOS It is hereditary…
~
* Being fat because with PCOS is not your fault! … You have a medical condition wreaking havoc through your whole body from the hormone imbalance…
~
* Exercise and diet alone will not work! Infact, you can starve yourself and maybe lose a few pounds, you can beat yourself exercizing and see minimal results… Why? Your hormones are messed up!
_
* If a doctor tells you to exercise and diet, YOU NEED TO RUN FROM THAT DOCTOR!!! They know nothing about PCOS! *
~
* IF your doctor wants more tests done than on my Test List ask why…. Ask why if most of the tests from my list are not done… Plus have your doctor write the reasons you need tests not covered by your insurance to make them get covered by insurance companies!
~
* FACT: A Bristol Myers Squibb rep made me aware they know doctors today are not finishing their internships… They are being thrown in to practice due to lack of MD’s, etc…
* BE AWARE of undiagnosed ~ misdiagnosed ~ overmedicated ~ malpractice cases to be increased!
* IF you ever get bad (expired, bad shelf storage system, broken pills, etc…) drugs call the drug company 1st! Explain the scenario… Then call your doctor if the drug company is not replacing them… The drug company will think twice in giving the doctor that drug…
~
* FACT: Your Pharmacist is your new best friend… Take your drugs, etc… and sit down with them… They are trained in reactions, dosages, etc… Trust them – they KNOW!
~
* Serum Insulin Level blood test is a “KEY” in knowing if you can lose weight normally…
~ The level must be 11 or less in order for you to lose weight….
~ IF 12 and higher, you will never lose weight…
~
* FYI: The 1st 10-15 lbs is water weight…
~
* PCOS women die at early ages, 40’s through 60’s… Research shows it and due to heart disease or cancer… ~Your life is at stake here!
~
* Most women are misdiagnosed – Most diagnosed years ago with a thyroid disorder had PCOS and/or both…
~
* YOU are not alone… PCOS is a silent epidemic affecting so many women that have it and don’t know it!!!!!! Pass the PCOS word on…
~
* PCOS Ratio Factor – The ratio of luteinizing hormone to follicle stimulating hormone (LH: FSH ratio, a measure of the health of the ovaries. Most pre-menopausal women have a ratio close to 1:1 with FSH values slightly greater than LH. The higher the LH: FSH ratio the greater the likelihood of PCOS. Levels of LH higher than FSH suggests PCOS. High FSH levels suggests the ovary is running out of eggs. Some doctors believe that an LH: FSH greater than 2:1 or 3:1 indicates PCOS.
~
* PCOS is a silent epidemic – Most women have it and don’t know it! Pass the PCOS word on to every woman you know… You will be saving their life or that of someone you don’t know…
~
* Syndrome X is what men are diagnosed with… They may have symptoms like you minus the female specific ones… Men have to demand they get this diagnosis, why, like PCOS, doctors are naive to it…
~ My case: Exhubby has alot of the same symptoms i do… He has yet to be diagnosed with Syndrome X… He can not lose the tummy fat regardless of what he does…
~
* Diagnosed with depression
may be a fatigue problem or hormone imbalance or something else… SYMPTOMS do MATTER!!!! Google your symptoms…
~
* MINERALS:
Have all your minerals checked by a hair sample…Lack of or too much all cause medical conditions! Eat the foods to replenish minerals…
~ FACT – Doctors check blood, which if something shows up in your blood, your body is starting to die inside!
~
* Gastric Bypass
– Think twice! Have your hormones tested first… Have the Serum Insulin Level test … Look at my Symptoms List… If you still have the surgery, there is no quarantee your PCOS will disappear!… Infact, you are warned not to have the surgery because it will screw your hormones up…
~
FYI:
* Medical Records:
Keep track of your symptoms, drugs and actual medical records… Your history is important!
~
* YOU control your treatments with/or without your doctor… I say this because some women choose the natural way… Plus, due to most doctors not knowing much about PCOS, you have to know the treatments available for PCOS… You need to keep records, you know what works or doesn’t… You will know your body from PCOS if you don’t already…
~
* PCOS Lady: I feel if a doctor does not work with you, does not know the numerous treatments for PCOS, does not listen to you, etc… (Your journey will encompass more, hopefully not) … Then i take the stand i am being mistreated medically thereby being hurt by that doctor… That’s against the medical oath every doctor takes! Partial quote: “1st do no harm….”
~
* PCOS research is ongoing… Symptoms are being added continuously… RLS – Restless Leg Syndrome was added abit ago… Rosacea was added before RLS…
~
LINKS:
http://www.unhaggardhousewife.com/ … PCOS info, natural home remedies on topics as well… Worth a look!
~
www.PCOSCoach.com … PCOS Coach is an informative PCOS site with a newsletter, books she wrote, news and a few links… 3/2012 under construction
~
www.SoulCysters.net … Soul Cysters is a huge PCOS forum, free to join and highly informative…
Forum: http://www.soulcysters.net/forum.php
~
http://www.pcosupport.org/ … PCOS Association runs these email forum lists… 1st hand experiences… You ask questions and get honest answers…
Forum: http://www.pcoscommunity.com/
~
A separate LINKS page will be added…

November 17, 2008

Nov ’08 Research: Treatments, Causes, Risks

Posted in RESEARCH tagged , , , , , , , , , , , at 12:41 am by PCOSLady

New Studies Examine Treatments, Causes and Risks for
Women with PCOS

~
Toronto, Canada, June 21, 2000 – New research presented today on treatments, causes and risks
associated with Polycystic Ovary Syndrome(PCOS)
, a disease that effects between five and 10 percent of reproductive aged women, offers a glimmer of hope to the millions of women who suffer from the disease. The research was presented today in a panel at ENDO 2000, The Endocrine Society’s 82nd Annual Meeting, which is taking place in Toronto from June 21-24. The new studies examine several areas of PCOS, including a possible gene that triggers PCOS, new treatments for the disease, the relationship between diet and PCOS and the risk of heart disease in women with PCOS….
~
http://www.emergen.com/pages/research/pcos.html
~
Two of the studies that were presented examined new treatments for women with PCOS. One study found that women with PCOS who reduced their dietary fat might improve some of their reproductive parameters. Another study of adolescent girls with PCOS found that treatment with metformin, a medicine that decreases the body’s requirement for insulin, improves irregular or absent periods, a symptom of PCOS in young girls; lessens body hair and acne; and promotes weight loss…. “We have shown that metformin, which is typically a diabetes treatment, is effective in treating young women with PCOS,” said Dr. Ken Lee Jones, an endocrinologist at the University of California, San Diego who presented the research on metformin. “The new information that is presented today will help improve the quality of life for the women throughout the world who suffer from this disease.” … Dr. Walter Futterweit and Dr. Yaron Tomer,
endocrinologists at Mount Sinai Medical Center in New York, presented a study that found an association between a marker near the insulin receptor gene and PCOS. Previous research has found that PCOS is hereditary. The new research discovered evidence that the insulin receptor gene, or a nearby gene, may cause the tendency for women to inherit PCOS…. “This type of research will ultimately lead to better diagnosis and treatment for women with PCOS,” said Dr. Tomer….
~
Additionally, the research suggests that the inheritance of PCOS is caused by subtle changes in the insulin receptor gene, which may alter its function in the ovaries…. “We hope that these findings will enable us to better understand the mechanisms leading to PCOS,” said Dr. Futterweit…. Two of the other studies examined risk factors for women with PCOS, including insulin resistance and heart disease. One
study, which was presented by Dr. David Ehrmann, an endocrinologist at the University of Chicago, found that women with PCOS function near their maximum ability to secrete insulin in response to glucose. According to this new research, any further reductions in insulin sensitivity would be met with inadequate compensation in insulin secretion…. Dr. Rose Christian, a clinical research fellow
at the Mayo Clinic, reported on additional research that points to an increased risk of coronary heart disease for women with PCOS. Researchers found that coronary artery calcium, a marker for atherosclerosis, is more common and extensive in women with PCOS than in ovulatory women of similar age,
weight and risk factors…. “Our research showed that women with PCOS are as likely to develop coronary calcium as men of the same age,” said Dr. Christian. “Normally, coronary calcium and heart disease are three to four times more common in young men than in women of the same age.” … “PCOS is a common yet, silent disease that affects thousands of women,” said Dr. Lisa Fish, an endocrinologist at Park
Nicollett Medical Center in Minneapolis, Minnesota. “These studies provide new options to women with PCOS in treating their illness and also offer new information on risks that are associated with the it, such as heart disease. In addition, this research looks into the genes that may cause PCOS and its relationship to diabetes.” … Based in Bethesda, Maryland, The Endocrine Society consists of over 9,000 scientists and physicians in more than 80 countries. Founded in 1916, The Endocrine Society is the world’s oldest, largest, and most active organization devoted to research on hormones, and the clinical practice of endocrinology. Together, these physicians, scientists, educators, nurses, and students who
make up the organization’s membership, represent all basic, applied, and clinical interests in endocrinology. To learn more about The Endocrine Society, and thefield of endocrinology, visit our web site at www.endo-society.org…. New Directions in the Treatment of Polycystic Ovarian Syndrome by Ellen
Friedman Bender … Polycystic Ovarian Syndrome (PCOS) is a hormonal disorder affecting between 5 percent and 10 percent of women of reproductive age. Although many people correctly associate PCOS with impaired fertility
– chronic anovulation and hyperandrogenism (elevated male hormones) are two of its cardinal symptoms, it is more than an infertility disorder. Increasingly, PCOS is being recognized as a major women’s health problem because of the havoc it wreaks on the endocrine system. Many women with PCOS suffer from endocrine abnormalities including insulin resistance which affects the bodies ability to metabolize
sugar and fat….Significantly, according to a research study, premenopausal women who have the disorder are seven times more likely to suffer from adult onset diabetes than women without PCOS. In addition, over time, many women with PCOS develop elevated levels of cholesterol and triglycerides so that here is a greater risk of heart attack and stroke for women in their forties and fifties. Moreover, because of their irregular menstrual cycles, women with PCOS are at greater risk for endometrial cancer. Women with PCOS also frequently encounter self- esteem and body-image issues arising from other frequent symptoms of the disorder including hirsutism (excess facial and body hair),obesity, acne and male-pattern baldness… Traditionally, treatment for PCOS has focused on individual symptoms instead of the syndrome as a whole. Thus, a woman with PCOS who was trying to get pregnant might be given fertility drugs such as clomid
or pergonal. A woman in her twenties might be given oral contraceptives to regulate her menstrual cycle or provera to periodically shed the lining of her uterus. Another woman might be given spironolactone to inhibit hair growth. But recent research suggests that there may be lifestyle changes and medications that by attacking the insulin resistance, actually treat the syndrome as a whole…. At the very least,
some doctors recommend that their PCOS patients follow a carbohydrate-restricted diet and increase their exercise level. But the cutting edge research in PCOS is in the area of insulin sensitizing drugs. Recent studies have found that insulin sensitizing drugs given to type 2 diabetics, such as metformin, may also benefit women with PCOS. In one study, recently reported in the New England Journal of Medicine, an insulin sensitizing drug called INS-1 not only induced ovulation in 86% of the PCOS patients in the study,
it also reduced their triglyceride and blood pressure levels, lowering their risk for cardiovascular disease. At the moment, however, none of these insulin sensitizing agents are FDA approved for the treatment of PCOS and some of them have unpleasant side effects…. Ellen Friedman Bender co-chaired
the American Infertility Association’s recent conference on PCOS, “Understanding Polycystic Ovarian Syndrome: A Reproductive and Metabolic Disorder.” A version of this article appeared in the November 1999 issue of the Women’s O.W.N. of NYU Medical Center newsletter….
~
Treatment Options For PCOS
This information is provided for informational purposes only and is in no way meant to replace advice from a qualified medical professional…. Until recently, only the symptoms of PCOS – hirsutism, acne, infertility – could be treated. In the past few years, however, there has been a great deal of research pointing to excess production of insulin and resulting insulin resistance as the root of the problem….
Treatment With Insulin-Sensitizing Medications – The Newest Option A number of recent studies have shown
that treating women with PCOS with insulin-lowering medications such as metformin (also known as
Glucophage), Avandia (rosiglitazone) and Actos (pioglitazone), used to treat adult-onset diabetes,
can not only reduce the risks of heart disease and diabetes in women with PCOS by treating the underlying
problems with insulin production and usage, but also relieve many of the bothersome symptoms and even
make weight loss possible.1, 2
~
(Please note that these are not weight-loss drugs; women whose weight problems stemmed from insulin resistance may lose weight when the problem is corrected.)
~
These drugs do not lower blood sugar and so are generally safe even for those with hypoglycemia3, but there may be side effects. Metformin often causes diarrhea and/or nausea, especially for the first few weeks and when the dosage is increased. This is most problematic if it’s taken without food; these problems may be minimized by taking it halfway through a meal. A rare side effect is lactic acidosis, which may be fatal if not detected. Rezulin (troglitazone) was also used for this purpose until recently, but has been taken off the market after reports of liver abnormalities and even a handful of
deaths in some people who were taking it. Avandia and Actos are chemically related to Rezulin, but the effective dosages are far lower (4-8 mg/day of Avandia or 45 mg/day of Actos vs. 200-400 mg/day of Rezulin), making liver complications less likely. In clinical trials involving over 4500 patients, there have been no reports of Avandia-related liver toxicity or related problems4, 5; there have also been no reports of such complications from Actos4, 6 Even so, the FDA has recommended that patients who already have elevated liver enzyme levels be monitored regularly. Some people who take Avandia or Actos experience
a slight weight gain. (This hasn’t been my experience, though – I’ve actually lost several pounds in the last few months.) It is important to be aware that all of these medications are currently only approved by the FDA (in the US – I’m not entirely sure of their approval status in other countries) for the treatment of diabetes. There is a lot of convincing research showing that most if not all cases of PCOS can be improved by treating insulin resistance, and these drugs treat diabetes by treating insulin resistance. So, they’re likely to be helpful to many women with PCOS, and doctors are allowed to prescribe an approved drug for any purpose they wish, but some (especially those who aren’t up to date on the new research) may not be willing to do this. I’m working on writing up some information about d-chiro-inositol, the first medication being studied specifically to treat PCOS-related insulin resistance, but I want to do more research before I post anything here. In the meantime, check out Ovulatory and Metabolic Effects of d-Chiro-Inositol in the Polycystic Ovary Syndrome. This is an abstract of an article that appeared last year in the New England Journal of Medicine summarizing the findings of a study of this drug in women with PCOS….
~
Birth Control Pills
Birth control pills treat a few of the symptoms of PCOS. They usually bring on a period each month (though some women with PCOS do not have regular periods even while taking birth control pills) which is important for women who do not have regular cycles because lack of menstruation puts a woman at higher risk for endometrial cancer. Some women find that hair problems either lessen or stop getting worse while on the pill, particularly with Diane-35 or Dianette (which contains cyproterone acetate, an anti-androgen), which is available in some countries in Europe and also in Ausralia and New Zealand but has not been approved in the United States. Acne may improve as well. Weight gain is highly variable –
for some women weight gain may stabilize while on the pill; for others it may get worse. Changing brands may help if you find yourself gaining weight or having other unpleasant side effects. The triphasic birth control pills, such as Ortho Tri-Cyclen, may be problematic in that the estrogen dose they provide in the early part of the cycle may be too low to prevent women with PCOS from developing follicles, possibly resulting in a greater number of cysts on the ovaries.1 …
~
Treating Hirsutism
Hirsutism can an extremely difficult and emotional issue in a society where women are expected to be smooth and hairless. Shaving, plucking, waxing, electrolysis and laser hair removal treatments may work in many cases but can be, depending on the method, time-consuming, messy, painful and/or very
expensive. Spironolactone (brand name Aldactone), if taken over a period of time, will stop new hair growth in many women with hirsutism and may possibly decrease existing growth for some. In countries where Diane-35 has been approved, it may be prescribed help with hair problems….
~
Provera
Provera or other forms of synthetic progesterone are often prescribed to women experiencing amenhorrea
(lack of periods). It’s common for a Provera-induced period to be more heavy or painful than usual, but it’s important that something be done to cause regular menstruation because prolonged amenhorrea may
increase a woman’s risk for endometrial cancer. This doesn’t mean that if you haven’t had a period
for a very long time that you are destined to get cancer, but it does introduce a higher than usual risk. Some women have had success using progesterone cream as an alternative to Provera….
~
1. Kidson, Warren. Polycystic ovary syndrome: a new direction in treatment. MJA 1998; 169: 537-540.
2. Hopkinson, Zoe E. C. et al. Polycystic ovarian syndrome: the metabolic syndrome comes to gynaecology, BMJ 1998;317:329-332
3. Perloe, Mark. Polycystic Ovarian Syndrome: Treatment With Insulin-Lowering Medications.
4. Fonseca, Vivian A. Overcoming Insulin Resistance and Preventing Cardiovascular Disease in Diabetes: The Contributions of the Thiazolidinediones.
5. Avandia Shows Promising Results in Combination Therapy
6. Actos Approved By FDA For Type II Diabetes
~
April 28, 1999
~
New Drug May Help Women With Infertility Syndrome An investigational drug that helps insulin to function more efficiently appears to combat infertility in women with polycystic ovary syndrome (PCOS), the most common cause of female infertility, according to a research team funded in part by the National Institute
of Child Health and Human Development (NICHD). The drug, D-chiro- inositol, occurs naturally in fruits and vegetables and appears to have no side effects in the comparatively small number of PCOS
patients who took part in this preliminary trial….
~
The study, conducted by researchers at Virginia Commonwealth University (VCU) in Richmond, appears in the April 29 issue of The New England Journal of Medicine….
~
“These early results show a lot of promise,” said Dr. Donna Vogel, Associate Chief for Clinical Research in NICHD’s Reproductive Sciences Branch and NICHD program officer for the study. “Dr. Nestler and his
colleagues have shown that a substance naturally produced by the body to assist in insulin action promotes ovulation in the majority of PCOS patients who take it.” …
~
PCOS affects from 5 to 10 percent of American women of reproductive age (as many as 5 million in all), explained the study’s principal investigator, John E. Nestler, M.D., chairman of endocrinology at
VCU’s Medical College of Virginia. The ovaries of women with PCOS appear to be filled with numerous small cysts. The cyst-like appearance results from an accumulation of immature ovarian follicles, the bubble-like structures which, upon maturation, rupture and give rise to the egg cell….
~
The features of PCOS may include failure to ovulate or menstruate, abnormally high levels of insulin, obesity, high blood pressure, hardening of the arteries, and high triglyceride levels. (Triglycerides are fatty substances used for energy storage, and high triglyceride levels may increase the risk for coronary artery disease.) PCOS patients also have high levels of the male hormone testosterone, which may cause them to grow excess facial or body hair….
~
* “PCOS is not just a reproductive disorder; it’s a major health concern for women who are affected,” Dr. Nestler said. “This is a promising new drug because not only does it dramatically improve ovulation, it improves a woman’s overall health.” …
~
Dr. Nestler added that, traditionally, physicians have been able to treat only the symptoms of PCOS, and not eliminate its cause. For example, antiandrogens were prescribed to block the action of testosterone and reduce excessive hair growth. Birth control pills were used to regulate the menstrual cycle, and when the women sought to have children, they were treated with fertility drugs–either alone or in combination with in vitro fertililzation….
~
Roughly two years ago, however, Dr. Nestler and his colleagues were successful in reducing the PCOS symptoms of a group patients by treating them with the drug metformin, used to treat insulin resistance in patients with adult onset (type II) diabetes. (Insulin resistance is the failure of cells to respond to insulin properly). Metformin increases the body’s sensitivity to insulin and allows the body to use insulin more efficiently. Troglitazone, another insulin- sensitizing agent, has similar effects in PCOS patients. * …
~
Although both drugs do restore ovulation, both have a number of side effects. Metformin, for example, may cause diarrhea, nausea, and loss of appetite, and Troglitazone may be toxic to the liver….
~
The current findings strongly suggest that PCOS results from a failure to use insulin properly. Presumably, Dr. Nestler said, this failure causes insulin levels to rise. The high insulin levels, in turn, cause a variety of other effects, such as high blood pressure, hardening of the arteries, and high triglyceride levels. Insulin also appears to have an effect on the ovaries, causing them to produce high levels of testosterone and similar compounds, which halt egg maturation and interfere with the menstrual cycle….
~
In the current study, the researchers followed 44 obese women with PCOS; half received D-chiro-inositol, and half received a placebo. Of the 22 women who received the study drug, 86 percent ovulated, compared with only 27 percent of the women in the placebo group. Women who received D-chiro-inositol also saw improvements in insulin, blood sugar, blood pressure, testosterone and triglyceride levels. No side
effects were reported….
~
Dr. Nestler explained that the body uses D-chiro-inositol to manufacture the D-chiro-inositol mediator, which allows the cell toprocess glucose after insulin binds to the cell’s surface. According
to Dr. Nestler, the research offers insight into the possible cause of insulin resistance in women with PCOS, which previously had been unknown. A PCOS patient’s insulin resistance could be due, in part, to
a D-chiro-inositol deficiency….
~
NICHD is currently funding a trial of D-chiro-inositol in a large number of patients to further ascertain its safety and effectiveness. The drug is also being tested in patients with type II diabetes.
~
The study drug is manufactured by INSMED Pharmaceuticals, Inc., which develops products to detect and treat insulin resistance. The research is funded by an NIH Small Business Innovation Research Grant. These
grants are given to independently owned and operated U.S. companies that have fewer than 500 employees….
~
Polycystic Ovarian Syndrome
New Thought on an Old Disease
Polycystic Ovarian Syndrome (PCOS) has been a subject of intense interest and research since it’s initial description by Drs. Stein and Levinthal in the 1930′s. However, it was not until the 1980′s that an
association between this syndrome and insulin resistance was discovered, and only in the last several years that the benefit of insulin sensitize therapy in treating this condition has become known. Hence, the recent flurry of articles appearing not only in scientific journals but also in the lay press….
~
Why all the fuss? Probably because virtually everyone has a friend, relative or acquaintance who is affected with this disease. It is seen in 5-9% of reproductive age women, making it arguably the most common endocrine abnormality in this age group….
~
In spite of decades of research and volumes of material written on PCOS, there is not a universally agreed upon definition. The reasons for this is that the condition is a syndrome rather than a single
specific disease intensity. In other words, there are many discreet abnormalities, which may cause women to develop this syndrome, and each has certain unique features. However, although most of the “classic” signs or symptoms of PCOS are present in little more than half of women with this disease, irregular cycles with absent of infrequent ovulation is a prerequisite for labeling a patient with this diagnosis. Hair growth, acne, obesity, and the various hormonal and biochemical abnormalities associated with this condition are usually absent in at least a third of patients diagnosed with this condition….
~
Traditional therapies for Polycystic Ovarian Syndrome include bilateral ovarian wedge resection (now largely replaced by medical therapy or laparoscopic ovarian diathermy) contraception if patient does not wish to conceive, and clomiphene citrate if the patient is desirous of conception….
~
For patients who desire cycle control or relief from acne or hirsutism, oral contraceptives are the first line of management. Clomiphene citrate, which is an antiestrogen, can induce ovulation in PCOS patients by altering the natural secretion of ovulation enhancing hormones. However, only 60-80% of women with Polycystic Ovarian Syndrome will achieve regular spontaneous ovulation with this drug, and only about half of that number will ultimately conceive. The reason for this discrepancy between ovulation and pregnancy rates is not fully understood….
~
More recently, the role of insulin resistance in this condition has become better understood. In some individuals, insulin resistance is probably responsible for the development of PCOS. In others, it is
merely an association, linked either to obesity or genetic factors. There is a tremendous amount of research presently being conducted in this arena….
~
Of most significance to our patients with this condition, the role of insulin sensitizer therapy has become well known. There are three such medicines in used today, the common names of which are Actos, Avandia, and Glucophage. These medications allow the cells to respond more normally to the body’s insulin secretion which leads to a decrease in insulin production by the pancreas. The resulting decline in insulin levels affect a number of other pathways, ultimately improving a woman’s overall hormone balance and helping her to achieve ovulation more readily. In some women, insulin sensitizer therapy alone will
allow women with PCOS to ovulate and conceive. In others, medicines such as clomiphene citrate are still necessary. However, we now can help such women to ovulate with lower doses of clomiphene, and some
women who could not previously ovulate even with high and prolonged doses of Clomiphene can now conceive without having to resort to expensive injectable medications. Therefore, the extreme usefulness of
these medications in the treatment of this condition have become recognized as the first major medical advance in many years….
~
Not all women with PCOS have insulin resistance, and many who do have only a mild problem, which would probably not benefit from use of insulin sensitizer therapy. Often, these women may achieve similar or
better results using other methods such as weight loss and exercise. Adjunctive medications such as Tamoxifen or Decadron, or injectable menotropins may also be used with excellent results. Finally, ovarian
diathermy, in which the ovaries are treated with electrical energy during an outpatient laparoscopic procedure, produces excellent ovulation and pregnancy rates. It is beyond the scope of this article
to delineate the situations which would favor one treatment modality over another….
~
We have also become increasingly aware that there are sufficient long-term complications of insulin resistance and polycystic ovarian syndrome. During pregnancy, these patients display a higher incidence
of gestational diabetes, a potentially serious condition for the mother and fetus. Further on down the road it appears that women with PCOS are at significantly increased risk for hypertension, Type II
diabetes, and cardiovascular disease. There is currently much interest and research in this area, but as yet little information on how these potential complications are best avoided….
~
If you have or think you may have polycystic ovarian syndrome or insulin resistance, see your physician, or your infertility specialist for testing. Further details may be found on our web site, or through
national organizations such as Resolve or American Society for Reproductive Medicine…..
~
Future Research
——————————————————————————–
The role of insulin sensitizers in the long-term treatment of PCOS is still relatively new and hotly debated. More research is being conducted to determine the safety and efficacy of these treatments
[3]….http://pbl.cc.gatech.edu/mindy/952

It has also been found that PCOS is highly genetic. By studying families where PCOS is seen in several women, studies will hopefully be able to identify the gene(s) contributing to this disease. Dr.
Andrea Dunaif, Chief of the Division of Endocrinology, Metabolism, and Molecular Medicine at Northwestern University Medical School and a member of the Advisory Board for the Polycystic Ovary Syndrome Association, is the Principal Investigator of an ongoing National Institutes of Health-funded study examining the genetics of PCOS. She is recruiting women with PCOS (diagnosed or undiagnosed) and their
family members to study the genetics of this syndrome….
~
http://hsc.virginia.edu/medcntr/centers/crr/

March 13, 2008

My Original Blog Links…

Posted in LINKS tagged , , at 12:20 am by PCOSLady

My blog links to original posts….
Hormonal Health Profile     http://pcoslady.blogdrive.com/archive/25.html
 Project PCOS…   http://pcoslady.blogdrive.com/archive/24.html
 SYNDROME O   http://pcoslady.blogdrive.com/archive/23.html
 Info on Glucophage…   http://pcoslady.blogdrive.com/archive/21.html
 Info on Metformin…   http://pcoslady.blogdrive.com/archive/22.html
 New PCOS Treatment Guidelines.       http://pcoslady.blogdrive.com/archive/20.html
 FACTS..FYI..LINKS..INFO   http://pcoslady.blogdrive.com/archive/19.html
 Metobolic Syndrome (Syndrome X        http://pcoslady.blogdrive.com/archive/17.html
 COMMENTS: Welcome here…   http://pcoslady.blogdrive.com/archive/16.html
 MY PCOS STORY…   http://pcoslady.blogdrive.com/archive/15.html

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