September 27, 2012

Insulin Sensitivity Gene Found – PTEN

Posted in CANCER, RESEARCH tagged , , , , , , , , , , , , , , , , , , , , at 6:56 pm by PCOSLady

Insulin Sensitivity Gene Found – PTEN
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PCOS Lady:
Look into having your PTEN gene level tested…
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http://www.nejm.org/doi/full/10.1056/NEJMoa1113966
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PTEN Mutations as a Cause of Constitutive Insulin Sensitivity and Obesity
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Background
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Epidemiologic and genetic evidence links type 2 diabetes, obesity, and cancer. The tumor-suppressor phosphatase and tensin homologue (PTEN) has roles in both cellular growth and metabolic signaling. Germline PTEN mutations cause a cancer-predisposition syndrome, providing an opportunity to study the effect of PTEN haploinsufficiency in humans.
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http://mypcos.info/1/scientists-find-insulin-sensitivity-gene-may-lead-to-new-diabetes-treatments/
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Scientists find insulin sensitivity gene, may lead to new diabetes treatments
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The PTEN gene encodes for an enzyme that is part of the insulin signalling pathway in the body. It is known to have a role in controlling the body’s metabolism, and to play a part in cell growth. The Oxford team was interested in learning more about this dual role.
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There is an inherited genetic condition called Cowden syndrome caused by faults in the PTEN gene. It is very rare and is thought to affect perhaps one in 200,000 people, with around 300 people with the condition in the UK. PTEN’s role in cell growth sees people with Cowden syndrome develop many benign polyps in their skin, mouth and bowel, and have a higher risk than the general population of developing breast cancer, thyroid cancer and womb cancer.
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Please read her entire page on the PTEN gene… Easier to understand for you…
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GOOGLE:
PTEN
Cowden Syndrome
thyroid cancer PTEN
breast cancer PTEN
womb cancer PTEN
insulin PTEN
insulin sensitivity
insulin sensitivity PTEN
Diabetes PTEN
Germline PTEN
type 2 diabetes PTEN
obesity PTEN
cancer PTEN

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